ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or continue ADHD medications during breastfeeding and pregnancy is a difficult decision for women suffering from the condition. There aren’t enough data regarding how exposure over time may affect the foetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication during the uterus don’t develop neurological conditions like impaired vision or hearing, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality research is needed.
Risk/Benefit Analysis
Women who are pregnant and take ADHD medication need to evaluate the benefits of using it against the potential risks to the fetus. The doctors don’t have the information to make unambiguous recommendations however they can provide information on risks and benefits to help pregnant women make informed decisions.
A study published in Molecular Psychiatry found that women who used safest adhd medication for adults medications in early pregnancy did not have an increased risk of fetal heart malformations or major structural birth defects. Researchers used a large sample-based case control study to assess the frequency of major structural defects in infants who were born to mothers who took stimulants during pregnancy. Clinical geneticists, pediatric cardiologists and other experts examined the cases to make sure that the classification was accurate and to eliminate any bias.
However, the researchers’ study was not without its flaws. The most important issue was that they were not able to differentiate the effects of the medication from the effects of the underlying disorder. This limitation makes it difficult for researchers to establish whether the few associations observed between the exposed groups were due to the use of medications or if they were confounded by comorbidities. Additionally, the researchers did not study the long-term effects of offspring on their parents.
The study did reveal that infants whose mothers had taken ADHD medications during pregnancy were at slightly greater risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or taken off their medication prior to or during pregnancy. This was due to central nervous system disorders. The higher risk of admission was not influenced by the stimulant medications used during pregnancy.
Women who were taking stimulant ADHD medication during pregnancy also had an increased risk of having a caesarean birth or having a baby born with an low Apgar score (less than 7). These increases appeared to be unrelated to the type of medication taken during pregnancy.
Researchers suggest that the small risks associated with the use ADHD medication during pregnancies in the early stages can be offset by greater benefits for mother and baby of continuing treatment for the woman’s disorder. Doctors should discuss with their patients about this and try to help them develop coping strategies that can lessen the impact of her disorder in her daily functioning and her relationships.
Medication Interactions
Doctors are increasingly confronted with the dilemma of whether to maintain treatment or stop it during pregnancy as more women are diagnosed with ADHD. Often, these decisions are made without any evidence that is clear and definitive regardless, so doctors must weigh what they know, the experiences of other doctors, and what the research says on the topic and their own best judgment for each individual patient.
Particularly, the subject of potential risks to the infant can be difficult. The research on this issue is based on observations instead of controlled studies and a lot of the results are contradictory. Additionally, the majority of studies limit their analysis to live births, which can underestimate severe teratogenic effects that cause abortion or termination of the pregnancy. The study that is discussed in this journal club addresses these limitations by looking at data from both live and deceased births.
The conclusion The conclusion: While certain studies have demonstrated a positive association between ADHD medications and the risk of certain birth defects, others have found no such relationship, and most effective adhd medication studies have a neutral or slight negative effect. In the end, a careful risk/benefit analysis must be conducted in every situation.
It isn’t easy, but not impossible, for women with ADHD to stop taking their medication. In a recent article published in the Archives of Women’s Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of loneliness. Furthermore, a loss of medication can affect the ability to perform jobs and drive safely, which are important aspects of daily life for many people with ADHD.
She suggests women who are unsure about whether to continue or discontinue medication due to their pregnancy consider the possibility of educating friends, family members, and coworkers on the condition, its impact on daily functioning, and the advantages of staying on the current treatment plan. It can also help a woman feel confident about her decision. It is important to note that some drugs can pass through the placenta so if the patient decides to stop taking her ADHD medication during pregnancy and breastfeeding, she should be aware that traces of the medication could be transferred to the infant.
Birth Defects and Risk of
As the use of ADHD medications to treat symptoms of attention deficit hyperactivity disorder (all adhd medications) grows as do concerns about the effects that the drugs could have on the fetuses. A recent study published in the journal Molecular Psychiatry adds to the body of knowledge about this subject. Utilizing two huge data sets, researchers were able to look at more than 4.3 million pregnancies and see whether the use of stimulant medications increased the risk of birth defects. Researchers discovered that although the overall risk is low, the first trimester ADHD medication use was associated with slightly higher risk of certain heart defects, like ventriculoseptal defects.
The researchers of the study found no association between early use of medication and other congenital abnormalities, such as facial clefting or club foot. The results are in line with previous studies which showed a small, but significant increase in the number of cardiac malformations among women who began taking ADHD medication prior to pregnancy. The risk was higher in the latter half of pregnancy, when a lot of women are forced to stop taking their ADHD medication.
Women who took ADHD medication in the first trimester were more likely to require a caesarean birth, have a low Apgar after delivery, and have a baby who needed breathing assistance when they were born. However the researchers of the study were unable to eliminate selection bias by restricting the study to women who did not have any other medical conditions that could have contributed to these findings.
The researchers hope their research will aid in the clinical decisions of physicians who encounter pregnant women. They suggest that although discussing risks and benefits is important, the decision to stop or maintain treatment should be based on the woman’s needs and the severity of her ADHD symptoms.
The authors also warn that, while stopping the medication is an option, it isn’t an option to consider due to the high rate of depression and other mental health issues for women who are expecting or who are recently post-partum. Furthermore, research suggests that women who choose to stop taking their medication are more likely to have difficulties adapting to life without them following the baby’s arrival.
Nursing
The responsibilities that come with being a new mother can be overwhelming. Women suffering from ADHD are often faced with a number of difficulties when they must manage their symptoms, attend doctor appointments, prepare for the birth of their child and adjust to a new routine. Many women choose to continue taking their ADHD medication during pregnancy.
The risk for nursing infant is low because the majority of stimulant medication passes through breast milk at low levels. However, the amount of medication given for adhd exposure to the infant can differ based on the dosage, frequency it is taken and at what time the medication is administered. In addition, different medications enter the baby’s system via the gastrointestinal tract or breast milk. The effect on a newborn’s health is not fully comprehended.
Because types Of adhd Medication the lack of evidence, some doctors might be tempted to stop taking stimulant drugs during a woman’s pregnancy. It is a difficult decision for the woman, who must weigh the benefits of taking her medication as well as the potential risks to the embryo. In the meantime, until more information is available, GPs can ask pregnant patients if they have a history of strongest adhd medication for adults or if they plan to take medication in the perinatal period.
Many studies have shown that women can continue to take their ADHD medication safely during pregnancy and while breast-feeding. In the end, many patients are choosing to do so and in consultation with their doctor they have discovered that the benefits of maintaining their current medication outweigh any risks.
It’s important for women with ADHD who are considering breastfeeding to seek a specialist psychiatrist’s guidance prior to becoming pregnant. They should discuss their medication with their physician and discuss the pros and cons of continued treatment, including non-pharmacological strategies. Psychoeducation is also required to help pregnant women suffering from ADHD be aware of the symptoms and the underlying disorder. They should also be educated about treatment options and strengthen the coping mechanisms. This should be a multidisciplinary effort including obstetricians, GPs, and psychiatrists. The pregnancy counselling should consist of the discussion of a treatment plan for both the mother and child, as well as monitoring for signs of deterioration, and the need for adjustments to the medication regimen.